OYAH INGREDIENT LIBRARY

L-arginine

L-arginine participates in nitric-oxide production, but oral supplementation produces variable cardiovascular and exercise results.

Evidence reviewUpdated 11 October 2026
LNitric oxide pathway / amino acid
Evidence signalBlood-pressure signal; inconsistent performance effect
Research focusBlood pressure, endothelial function and exercise
Key qualifierAmount, baseline health and co-supplementation

What it is

L-arginine is an amino acid and nitric-oxide precursor. Oral arginine undergoes substantial metabolism before reaching circulation, which helps explain why citrulline and arginine are separate interventions.

What human research suggests

Meta-analyses report modest average blood-pressure reductions in some populations. Exercise-performance findings vary by dose, training status and outcome. Cardiovascular biomarker findings do not establish better training performance.

HOW THIS RELATES TO OYAH

L-arginine in an OYAH formula.

The related product page shows the current ingredient list and directions. Compare those details with each paper before deciding how closely the evidence applies. OYAH does not claim that the finished formula was tested in the linked studies.

L-Citrulline & L-Arginine StackView L-Citrulline & L-Arginine Stack
Ingredient studyTests a defined ingredient, preparation and protocol.Finished-product evidenceWould require a clinical trial of the complete formula.Certificate of AnalysisReports the tests shown for a sample or lot; it does not establish benefit.
SAFETY & CONTEXT

What to consider before use.

Arginine may lower blood pressure and interact with nitrates, antihypertensives and erectile-dysfunction medicines. It can cause gastrointestinal symptoms and may trigger herpes recurrences in susceptible people. People after a recent heart attack should avoid it unless a clinician directs use.

This guide is educational and is not medical advice. Speak with a qualified healthcare professional about pregnancy, breastfeeding, medical conditions, medicines, surgery or persistent symptoms.

READ THE SOURCES

Follow the evidence.

Each link opens the publication, indexed record or government guidance. Study findings remain limited to the preparation and protocol researchers examined.

  1. L-arginine and blood pressure2022 dose-response meta-analysis · PMID 34967840 ↗
  2. Oral arginine and blood pressureMeta-analysis of double-blind trials · PMID 22137067 ↗
  3. Arginine and athletic performance2020 systematic review and meta-analysis · PMID 32370176 ↗
  4. Therapeutic benefits of L-arginineUmbrella review of meta-analyses · PMID 27660594 ↗
Current product directory

Know the product. Read the evidence.

Compare the current OYAH range, then open the product-specific evidence and ingredient guides. Ingredient studies do not establish the benefits of a finished OYAH formula.